Organic Chemistry II

This course deepens your understanding of the complex reactions and properties of organic molecules. Learn about a range of topics, including alcohols, ethers, and related compounds; oxidation and reduction reactions; among others.

What you’ll learn

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Organic Chemistry II

$79

Plus membership

3 Credits

All courses include:

eTextbooks

2 to 3-day turnaround for grading

Multiple chances to improve your grade

On-demand tutoring & writing center

Student support 7 days a week

$79

Plus membership

3 Credits

All courses include:

eTextbooks

2 to 3-day turnaround for grading

Multiple chances to improve your grade

On-demand tutoring & writing center

Student support 7 days a week

Organic Chemistry II

$79

Plus membership

3 Credits

About This Course

|
ACE Approved 2023

Taking Organic Chemistry II online will build on your foundational knowledge of organic chemistry to deepen your understanding of the complex reactions and properties of organic molecules.

download syllabus

What You'll Learn

Predict the appearance of product(s) of a dehydration reaction, Sn1 reaction, or epoxide ring opening.

Predict the appearance of product(s) of a alkene dihydroxylation or ozonolysis reaction.

Using the inscribed polygon method to determine if a compound is aromatic.

Predict the appearance of product(s) from a monosubstituted, disubstituted, or trisubstituted benzene with an electrophile.

Predict the appearance of all stereoisomers that form in a Grignard reaction.

Predict the appearance of stereoisomers that form in the intramolecular cyclization of a hydroxy aldehyde.

Rank benzoic acids in order of increasing acidity.

Determine the carboxylic acid and alcohol needed for a Fischer esterification.

Use retrosynthetic analysis in a reductive amination.

Use spectroscopy to identify compounds.

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Course Details

CHEM251

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Organic Chemistry II

Organic Chemistry II covers a wide range of topics, including alcohols, ethers, and related compounds, oxidation and reduction reactions, benzene and aromatic compounds, reactions of aromatic compounds, introduction to carbonyl chemistry, aldehydes and ketones, carboxylic acids and nitriles, and amines.

Prerequisites

There are no prerequisites to take Organic Chemistry II though we highly recommend concurrent enrollment in Organic Chemistry I (CHEM250).

Topic Objectives
Alcohols, Ethers, and Related Compounds
  • Naming an acyclic alcohol using the IUPAC system
  • Using the Williamson ether synthesis to convert an alcohol to an ether
  • Determining when a carbocation rearrangement might occur
  • Drawing the products of a dehydration reaction when a 1,2-methyl shift occurs
  • Drawing the products of an SN1 reaction when a 1,2-hydride shift occurs
  • Deciding if an alcohol reacts by substitution or elimination
  • Determining the stereochemistry in the conversion of ROH to RCl
  • Drawing the product of an epoxide ring opening with a strong nucleophile
  • Drawing the product of an epoxide ring opening with an acid
Oxidation and Reduction
  • Determining the number of rings and pi bonds in a compound (C14H20) hydrogenated to a compound of molecular formula C14H26
  • Drawing the stereoisomers from alkene epoxidation with mCPBA
  • Drawing the products of dihydroxylation of an alkene
  • Drawing the products of an ozonolysis reaction
  • Identifying an alkene from ozonolysis products
  • Predicting the product of a Sharpless reaction
Benzene and Aromatic Compounds
  • Determining if a cyclic, planar compound is aromatic, antiaromatic, or not aromatic
  • Determining is a planar compound is aromatic, antiaromatic, or not aromatic
  • Determining if a planar heterocyclic compound is aromatic, antiromantic or not aromatic
  • Using the inscribed polygon method to determine if a compound is aromatic
Reactions of Aromatic Compounds
  • Classifying substituents as electron donating or electron withdrawing
  • Drawing the products from reaction of a monosubstituted benzene with an electrophile
  • Drawing the product(s) from reaction of a monosubstituted benzene with an electrophile
  • Drawing the product(s) from reaction of a disubstituted benzene with an electrophile
  • Divising a synthesis of a disubstituted benzene
  • Devising a synthesis of a trisubstituted benzene
Introduction to Carbonyl Chemistry: Organometallic Reagents; Oxidation and Reduction
  • Determining the starting materials for the preparation of an alcohol from an organolithium reagent and an ester
  • UDevisiing a synthesis of a ketone
  • Using a protecting group
  • Drawing the product that forms in the reaction of an a,betaunsaturated carbonyl compound with an organometallic reagent
AAldehydes and Ketones— Nucleophilic Addition
  • Drawing all stereoisomers that form in a Grignard reaction
  • Synthesizing Wittig reagents by a two-step procedure
  • Determining the starting materials for a Wittig reaction using retrosynthetic analysis
  • Using an acetal as a protecting group
  • Drawing the stereoisomers that form in the intramolecular cyclization of a hydroxy aldehyde
  • Determining the reactive OH group that forms an acetal when treated with an alcohol and acid
Alkyl Halides and Elimination Reactions
  • Comparing the stability of alkenes
  • Drawing all products and predicting the major product of an elimination reaction
  • Drawing the product of an E2 reaction of a halo-cyclohexane when loss of HX must be anti periplanar
  • Deciding if a β elimination reaction proceeds by an E1 or E2 mechanism
  • Deciding if a reaction proceeds by SN1, SN2, E1, or E2
  • Drawing the product(s) of a reaction with a 1° alkyl halide
  • Drawing the product(s) of a reaction with a 2° alkyl halide
Alkenes and Addition Reactions
  • Calculating degrees of unsaturation
  • Assigning E,Z in naming an alkene
  • Drawing the products of an addition reaction
  • Comparing the products of hydration of an alkene
Carboxylic Acids and Nitriles
  • Drawing the products of an acid-base reaction involving a carboxylic acid
  • Ranking benzoic acids in order of increasing acidity
  • Separating a carboxylic acid from an alcohol by extraction
  • Devising a synthesis
Carboxylic Acids and Their Derivatives-Nucleophilic Acyl Substitution
  • Determining whether a nucleophilic acyl substitution will occurs
  • Determining the carboxylic acid and alcohol needed for a Fischer esterification
Amines
  • Using retrosynthetic analysis in a reductive amination
  • Ranking arylamines in order of increasing basicity
  • Ranking N atoms in order of increasing basicity
  • Drawing the major and minor product formed from Hofmann elimination
  • Devising a synthesis using diazonium salts
  • Drawing the starting materials needed to synthesize an azo compound

Your score provides a percentage score and letter grade for each course. A passing percentage is 70% or higher.

Assignments for this course include:

  • Graded Exam 1
  • Graded Exam 2
  • Graded Exam 3
  • Graded Exam 4


The required eTextbook for this course is included with your course purchase at no additional cost.


Smith, Janice. Organic Chemistry. 7th ed., McGraw Hill, 2024. ISBN:9781264141531


Organic Chemistry students also take:

Organic Chemistry II Lab

Biochemistry

Biochemistry Lab

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